Ts(4¹⁷)2Lws
Chemically induced Allele Detail

Summary

• Symbol: Ts(4¹⁷)2Lws
• Name: trisomy 17, Chr 17 translocation to Chr4, Lewis 2; trisomy 17, Chr 17 translocation to Chr 4, Lewis 2
• MGI ID: MGI:3698135
• Synonyms: T2Lws
• Gene: Ts(4¹⁷)2Lws Location: unknown Genetic Position: Chr17, Syntenic

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Translocation
• Mutation details: Breakpoints for chromosome 17 span from E4 to the telomere where induced by treatment with ethylene oxide. This sequence was fused to chromosome 4, demonstrating breakpoints spanning from the centromere to 4A4. (J:10392)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ts(4 17 )2Lws Mutation: 1 strain or line available

References

• Original: J:10392 Lewis SE, et al., A new dominant neurological mutant induced in the mouse by ethylene oxide. Mutat Res. 1990 Apr;229(2):135-9
• All: 2 reference(s)