Atp6v0d2^tm1Ywc
Targeted Allele Detail

Summary

• Symbol: Atp6v0d2^tm1Ywc
• Name: ATPase, H+ transporting, lysosomal V0 subunit D2; targeted mutation 1, Yongwon Choi
• MGI ID: MGI:3698147
• Synonyms: Atp6v0d2^-
• Gene: Atp6v0d2 Location: Chr4:19876838-19922566 bp, - strand Genetic Position: Chr4, 7.67 cM
• Alliance: Atp6v0d2^tm1Ywc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117744
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced with a neo-GFP. (J:117744)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp6v0d2 Mutation: 29 strains or lines available

References

• Original: J:117744 Lee SH, et al., v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med. 2006 Dec;12(12):1403-9
• All: 5 reference(s)