Fhl1^tm1Chen
Targeted Allele Detail

Summary

• Symbol: Fhl1^tm1Chen
• Name: four and a half LIM domains 1; targeted mutation 1, Ju Chen
• MGI ID: MGI:3698169
• Gene: Fhl1 Location: ChrX:55777147-55838706 bp, + strand Genetic Position: ChrX, 30.06 cM, cytoband A6-A7.1
• Alliance: Fhl1^tm1Chen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63769
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Exon 1 was replaced with a lacZ and neo cassette. The absence of protein expression was confirmed by western blot analysis on ventricle extracts. (J:144736)

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fhl1 Mutation: 9 strains or lines available

References

• Original: J:63769 Chu P, et al., Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular system. Mech Dev. 2000 Jul;95(1-2):259-65
• All: 10 reference(s)