Adipor1^tm1Tka
Targeted Allele Detail

Summary

• Symbol: Adipor1^tm1Tka
• Name: adiponectin receptor 1; targeted mutation 1, Takashi Kadowaki
• MGI ID: MGI:3698268
• Synonyms: Adipor1^-
• Gene: Adipor1 Location: Chr1:134343116-134361089 bp, + strand Genetic Position: Chr1, 58.22 cM, cytoband E4
• Alliance: Adipor1^tm1Tka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117919
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo was inserted to replace exons 2, 3, and 4. (J:117919)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipor1 Mutation: 45 strains or lines available

References

• Original: J:117919 Yamauchi T, et al., Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med. 2007 Mar;13(3):332-339
• All: 6 reference(s)