Thoc1^tm2Dwg
Targeted Allele Detail

Summary

• Symbol: Thoc1^tm2Dwg
• Name: THO complex 1; targeted mutation 2, David W Goodrich
• MGI ID: MGI:3698313
• Synonyms: Thoc1^H
• Gene: Thoc1 Location: Chr18:9958176-9995486 bp, + strand Genetic Position: Chr18, 4.91 cM
• Alliance: Thoc1^tm2Dwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117869
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Hypomorph)
• Mutation: Insertion
• Mutation details: An FRT site flanked neomycin selection cassette was inserted into intron 5. LoxP sites were inserted into intron 5, upstream of the first FRT site, and intron 7. This allele is a hypomorph. (J:117869)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thoc1 Mutation: 46 strains or lines available

References

• Original: J:117869 Wang X, et al., An allelic series for studying the mouse Thoc1 gene. Genesis. 2007 Jan;45(1):32-7
• All: 4 reference(s)