Surf1^tm2Zev
Targeted Allele Detail

Summary

• Symbol: Surf1^tm2Zev
• Name: surfeit gene 1; targeted mutation 2, Massimo Zeviani
• MGI ID: MGI:3698399
• Synonyms: Surf^{loxP-NEO-loxP}
• Gene: Surf1 Location: Chr2:26803393-26806542 bp, - strand Genetic Position: Chr2, 19.1 cM
• Alliance: Surf1^tm2Zev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117871
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A floxed neomycin resistance cassette was inserted into exon 7. (J:117871)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Surf1 Mutation: 14 strains or lines available

References

• Original: J:117871 Dell'agnello C, et al., Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice. Hum Mol Genet. 2007 Feb 15;16(4):431-44
• All: 2 reference(s)