Mgat4a^tm1.1Jxm
Targeted Allele Detail

Summary

• Symbol: Mgat4a^tm1.1Jxm
• Name: mannoside acetylglucosaminyltransferase 4, isoenzyme A; targeted mutation 1.1, Jamey Marth
• MGI ID: MGI:3698839
• Synonyms: Mgat4a^delta
• Gene: Mgat4a Location: Chr1:37478421-37580097 bp, - strand Genetic Position: Chr1, 15.46 cM
• Alliance: Mgat4a^tm1.1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117542
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 7 was removed via cre mediated recombination, resulting in the disruption of the catalyitic domain and a frameshift followed closely by a translational termination signal. (J:117542)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mgat4a Mutation: 34 strains or lines available

References

• Original: J:117542 Ohtsubo K, et al., Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes. Cell. 2005 Dec 29;123(7):1307-21
• All: 3 reference(s)