Foxo4^tm1Rdp
Targeted Allele Detail

Summary

• Symbol: Foxo4^tm1Rdp
• Name: forkhead box O4; targeted mutation 1, Ronald DePinho
• MGI ID: MGI:3698869
• Synonyms: Foxo4^F, FoxO4^L
• Gene: Foxo4 Location: ChrX:100298134-100304479 bp, + strand Genetic Position: ChrX, 43.89 cM
• Alliance: Foxo4^tm1Rdp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118179
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 1 was flanked with loxP sites. This is the second major coding exon and encodes the C-terminal half of the full-length protein. (J:118179)

Disease models

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxo4 Mutation: 15 strains or lines available

References

• Original: J:118179 Paik JH, et al., FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 2007 Jan 26;128(2):309-23
• All: 61 reference(s)