Alms1^L2131X
Chemically induced Allele Detail

Summary

• Symbol: Alms1^L2131X
• Name: ALMS1, centrosome and basal body associated; L2131
• MGI ID: MGI:3699224
• Gene: Alms1 Location: Chr6:85564513-85679735 bp, + strand Genetic Position: Chr6, 37.48 cM
• Alliance: Alms1^L2131X page

Kidney abnormalities of Alms1^L2131X/Alms1^L2131X mice at 6 months of age

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This mutation causes premature truncation in exon 10, resulting in the coding of the N-terminal 2131 amino acids of the protein. (J:118221)

Disease models

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alms1 Mutation: 150 strains or lines available

References

• Original: J:118221 Li G, et al., A Role for Alstrom Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence. PLoS Genet. 2007 Jan 5;3(1):e8
• All: 1 reference(s)