Asprv1^tm1Tmts
Targeted Allele Detail

Summary

• Symbol: Asprv1^tm1Tmts
• Name: aspartic peptidase, retroviral-like 1; targeted mutation 1, Takeshi Matsui
• MGI ID: MGI:3699318
• Synonyms: mSASP^-
• Gene: Asprv1 Location: Chr6:86605216-86606692 bp, + strand Genetic Position: Chr6, 37.75 cM
• Alliance: Asprv1^tm1Tmts page

Wrinkle formation in Asprv1^tm1Tmts/Asprv1^tm1Tmts mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116504
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced the entire exon. Absence of protein was confirmed by immunoblot analysis. (J:116504)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asprv1 Mutation: 23 strains or lines available

References

• Original: J:116504 Matsui T, et al., Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation. J Biol Chem. 2006 Sep 15;281(37):27512-25
• All: 2 reference(s)