Gcnt3^tm1Jxm
Targeted Allele Detail

Summary

• Symbol: Gcnt3^tm1Jxm
• Name: glucosaminyl (N-acetyl) transferase 3, mucin type; targeted mutation 1, Jamey Marth
• MGI ID: MGI:3699606
• Synonyms: C2GnT2^F
• Gene: Gcnt3 Location: Chr9:69938778-69945370 bp, - strand Genetic Position: Chr9, 39.2 cM, cytoband D
• Alliance: Gcnt3^tm1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149909
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was used to place a floxed neomycin-thymidine kinase expression cassette downstream of the single coding exon, and a loxP site upstream. Transient Cre expression in targeted ES cells excised the neo cassette and left the floxed exon. (J:132967, J:149909)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gcnt3 Mutation: 25 strains or lines available

References

• Original: J:149909 Stone EL, et al., Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol. 2009 Jul;29(13):3770-82
• All: 2 reference(s)