Sulf1^tm1Clrm
Targeted Allele Detail

Summary

• Symbol: Sulf1^tm1Clrm
• Name: sulfatase 1; targeted mutation 1, Catherine L R Merry
• MGI ID: MGI:3699620
• Synonyms: mSulf1^-
• Gene: Sulf1 Location: Chr1:12762501-12931416 bp, + strand Genetic Position: Chr1, 3.35 cM
• Alliance: Sulf1^tm1Clrm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116527
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted into exon 2. Northern blot confirmed absence of transcript in mutants. (J:116527)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sulf1 Mutation: 112 strains or lines available

References

• Original: J:116527 Lamanna WC, et al., Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. Biochem J. 2006 Nov 15;400(1):63-73
• All: 7 reference(s)