Sulf2^tm1Clrm
Targeted Allele Detail

Summary

• Symbol: Sulf2^tm1Clrm
• Name: sulfatase 2; targeted mutation 1, Catherine L R Merry
• MGI ID: MGI:3699621
• Synonyms: mSulf2^-
• Gene: Sulf2 Location: Chr2:165915819-165997603 bp, - strand Genetic Position: Chr2, 86.31 cM, cytoband H3
• Alliance: Sulf2^tm1Clrm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116527
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted into exon 1. Northern blot confirmed absence of transcript in mutants. (J:116527)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sulf2 Mutation: 177 strains or lines available

References

• Original: J:116527 Lamanna WC, et al., Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. Biochem J. 2006 Nov 15;400(1):63-73
• All: 7 reference(s)