Hsp90b1^tm1.1Zhli
Targeted Allele Detail

Summary

• Symbol: Hsp90b1^tm1.1Zhli
• Name: heat shock protein 90, beta (Grp94), member 1; targeted mutation 1.1, Zihai Li
• MGI ID: MGI:3700024
• Synonyms: Hsp90b1^-
• Gene: Hsp90b1 Location: Chr10:86526705-86541308 bp, - strand Genetic Position: Chr10, 43.05 cM
• Alliance: Hsp90b1^tm1.1Zhli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118427
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre mediated recombination resulted in the removal of exon 1. (J:118427)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hsp90b1 Mutation: 35 strains or lines available

References

• Original: J:118427 Yang Y, et al., Heat Shock Protein gp96 Is a Master Chaperone for Toll-like Receptors and Is Important in the Innate Function of Macrophages. Immunity. 2007 Feb;26(2):215-26
• All: 5 reference(s)