Prdx3^{Gt(Betageo-puro)711Lex}
Gene trapped Allele Detail

Summary

• Symbol: Prdx3^{Gt(Betageo-puro)711Lex}
• Name: peroxiredoxin 3; gene trap 711, Lexicon Genetics
• MGI ID: MGI:3700138
• Synonyms: Mer5^-, PrxIII^-
• Gene: Prdx3 Location: Chr19:60852504-60862976 bp, - strand Genetic Position: Chr19, 56.52 cM
• Alliance: Prdx3^{Gt(Betageo-puro)711Lex} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118595
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector was integrated within the first intron. Western blot confirmed ablation of the locus. (J:118595)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx3 Mutation: 26 strains or lines available

References

• Original: J:118595 Li L, et al., Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun. 2007 Apr 13;355(3):715-21
• All: 5 reference(s)