Nr0b2^tm1Auw
Targeted Allele Detail

Summary

• Symbol: Nr0b2^tm1Auw
• Name: nuclear receptor subfamily 0, group B, member 2; targeted mutation 1, Johan Auwerx
• MGI ID: MGI:3700156
• Synonyms: L2, Shp^L2
• Gene: Nr0b2 Location: Chr4:133280687-133283847 bp, + strand Genetic Position: Chr4, 66.25 cM
• Alliance: Nr0b2^tm1Auw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118368
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exons 1 and 2. (J:118368)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr0b2 Mutation: 17 strains or lines available

References

• Original: J:118368 Volle DH, et al., The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. Genes Dev. 2007 Feb 1;21(3):303-15
• All: 5 reference(s)