Mtf2^Gt(XD143)Byg
Gene trapped Allele Detail

Summary

• Symbol: Mtf2^Gt(XD143)Byg
• Name: metal response element binding transcription factor 2; gene trap XD143, BayGenomics
• MGI ID: MGI:3700158
• Synonyms: Pcl2^-
• Gene: Mtf2 Location: Chr5:108213540-108256870 bp, + strand Genetic Position: Chr5, 52.41 cM
• Alliance: Mtf2^Gt(XD143)Byg page

Mutation origin

• Mutant Cell Line: XD143
• Germline Transmission: Earliest citation of germline transmission: J:118339
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: A gene trap vector was inserted between exons 4 and 5 and was predicted to produce a C-terminal truncation. (J:118339)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XD143	CC183417 ; (MGI Seq Detail)	5' RACE	Chr5:108228847-108229080 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  759 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtf2 Mutation: 314 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:118339 Wang S, et al., Polycomblike-2-deficient mice exhibit normal left-right asymmetry. Dev Dyn. 2007 Mar;236(3):853-61
• All: 2 reference(s)