Cd7^tm1Fabo
Targeted Allele Detail

Summary

• Symbol: Cd7^tm1Fabo
• Name: CD7 antigen; targeted mutation 1, Francisco A Bonilla
• MGI ID: MGI:3700571
• Gene: Cd7 Location: Chr11:120927573-120930244 bp, - strand Genetic Position: Chr11, 84.85 cM
• Alliance: Cd7^tm1Fabo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:45026
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 6 Kb segment of genomic DNA containing the entire coding region was replaced by a neo cassette. RT-PCR analysis confirmed the absence of RNA expression in homozygous thymocytes. (J:45026)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd7 Mutation: 15 strains or lines available

References

• Original: J:45026 Bonilla FA, et al., Targeted gene disruption of murine CD7. Int Immunol. 1997 Dec;9(12):1875-83
• All: 1 reference(s)