Fgfr2^tm1Wrst
Targeted Allele Detail

Summary

• Symbol: Fgfr2^tm1Wrst
• Name: fibroblast growth factor receptor 2; targeted mutation 1, Wolfgang Wurst
• MGI ID: MGI:3700773
• Synonyms: Fgfr2^lox
• Gene: Fgfr2 Location: Chr7:129764181-129868538 bp, - strand Genetic Position: Chr7, 73.19 cM
• Alliance: Fgfr2^tm1Wrst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118802
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 5 was floxed by the insertion of a floxed neo cassette and an additional loxP site 3' of exon 5. Subsequent removal of the floxed neo cassette from ES cells was achieved by transient cre expression. (J:118802)

Expression

In Mice Carrying this Mutation:

144 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr2 Mutation: 90 strains or lines available

References

• Original: J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
• All: 2 reference(s)