Dnajb1^tm1Kate
Targeted Allele Detail

Summary

• Symbol: Dnajb1^tm1Kate
• Name: DnaJ heat shock protein family (Hsp40) member B1; targeted mutation 1, Kazutoyo Terada
• MGI ID: MGI:3700841
• Synonyms: DjB1^-
• Gene: Dnajb1 Location: Chr8:84334822-84339282 bp, + strand Genetic Position: Chr8, 40.22 cM, cytoband C3
• Alliance: Dnajb1^tm1Kate page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118757
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A 1.3Kb floxed neo cassette was inserted into exon 1, 40bp downstream from the initial ATG. Northern and western blot analysis of testes tissue confirmed the absence of RNA and protein expression in homozygous mice. (J:118757)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnajb1 Mutation: 21 strains or lines available

References

• Original: J:118757 Uchiyama Y, et al., Heat shock protein 40/DjB1 is required for thermotolerance in early phase. J Biochem. 2006 Dec;140(6):805-12
• All: 1 reference(s)