Ywhaq^{Gt(RRR746)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Ywhaq^{Gt(RRR746)Byg}
• Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; gene trap RRR746, BayGenomics
• MGI ID: MGI:3700919
• Synonyms: 14-3-3tau^-
• Gene: Ywhaq Location: Chr12:21440330-21467437 bp, - strand Genetic Position: Chr12, 8.31 cM
• Alliance: Ywhaq^{Gt(RRR746)Byg} page

Mutation origin

• Mutant Cell Line: RRR746
• Germline Transmission: Earliest citation of germline transmission: J:118280
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• A gene trap vector interrupted the locus. (J:118280)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRR746	CG784574 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ywhaq Mutation: 33 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:118280 Lau JM, et al., The 14-3-3tau phosphoserine-binding protein is required for cardiomyocyte survival. Mol Cell Biol. 2007 Feb;27(4):1455-66
• All: 2 reference(s)