H19^tm7Msb
Targeted Allele Detail

Summary

• Symbol: H19^tm7Msb
• Name: H19, imprinted maternally expressed transcript; targeted mutation 7, Marisa S Bartolomei
• MGI ID: MGI:3701075
• Synonyms: H19^delta4.2
• Gene: H19 Location: Chr7:142129267-142131883 bp, - strand Genetic Position: Chr7, 87.97 cM
• Alliance: H19^tm7Msb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118894
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to delete the 4.2 kb domain separating the endogenous transcription unit from the endodermal enhancers via cre-mediated recombination. (J:118894)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H19 Mutation: 12 strains or lines available

References

• Original: J:118894 Verona RI, et al., Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression. Genomics. 2004 Jul;84(1):59-68
• All: 1 reference(s)