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Ltb4r1tm1Tksh
Targeted Allele Detail
Summary
Symbol: Ltb4r1tm1Tksh
Name: leukotriene B4 receptor 1; targeted mutation 1, Takao Schimizu
MGI ID: MGI:3701260
Synonyms: BLT1-
Gene: Ltb4r1  Location: Chr14:56003419-56005951 bp, + strand  Genetic Position: Chr14, 28.19 cM
Alliance: Ltb4r1tm1Tksh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118995
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    A lacZ-neo was inserted into exon 2 of the locus. (J:118995)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ltb4r1 Mutation:  20 strains or lines available
References
Original:  J:118995 Terawaki K, et al., Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses. J Immunol. 2005 Oct 1;175(7):4217-25
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory