Eloa^tm1Aso
Targeted Allele Detail

Summary

• Symbol: Eloa^tm1Aso
• Name: elongin A; targeted mutation 1, T Aso
• MGI ID: MGI:3701319
• Synonyms: Elongin A ^-
• Gene: Eloa Location: Chr4:135730681-135748960 bp, - strand Genetic Position: Chr4, 68.34 cM, cytoband D3
• Alliance: Eloa^tm1Aso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119126
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo cassette replaced exons 8-10. Loss of RNA expression was confirmed by RT-PCR. (J:82946)

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eloa Mutation: 22 strains or lines available

References

• Original: J:119126 Miyata K, et al., Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A. Cell Death Differ. 2007 Apr;14(4):716-26
• All: 3 reference(s)