Crmp1^tm1Pako
Targeted Allele Detail

Summary

• Symbol: Crmp1^tm1Pako
• Name: collapsin response mediator protein 1; targeted mutation 1, Pappachan Kolattukudy
• MGI ID: MGI:3701338
• Synonyms: CRMP1
• Gene: Crmp1 Location: Chr5:37399402-37449507 bp, + strand Genetic Position: Chr5, 19.96 cM
• Alliance: Crmp1^tm1Pako page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119127
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An IRES-LacZ-neo cassette was inserted to replace part of exon 4. Western blot analysis confirmed the absence of protein. (J:119127)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Crmp1 Mutation: 45 strains or lines available

References

• Original: J:119127 Charrier E, et al., Transient alterations in granule cell proliferation, apoptosis and migration in postnatal developing cerebellum of CRMP1-/- mice. Genes Cells. 2006 Dec;11(12):1337-52
• All: 11 reference(s)