Wnt9a^tm2Chha
Targeted Allele Detail

Summary

• Symbol: Wnt9a^tm2Chha
• Name: wingless-type MMTV integration site family, member 9A; targeted mutation 2, Christine Hartmann
• MGI ID: MGI:3701350
• Synonyms: Wnt9a^lacZ
• Gene: Wnt9a Location: Chr11:59197754-59224378 bp, + strand Genetic Position: Chr11, 37.55 cM
• Alliance: Wnt9a^tm2Chha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119030
• Parent Cell Line: C1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An IRES-lacZ-FRT-neo cassette was inserted into exon 2 disrupting the open reading frame. Expression of the truncated transcript was confirmed by RT-PCR. (J:119030)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt9a Mutation: 17 strains or lines available

References

• Original: J:119030 Spater D, et al., Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006 Aug;133(15):3039-49
• All: 3 reference(s)