Igh-V^{tm1(Igh-Vx24)Hmb}
Targeted Allele Detail

Summary

• Symbol: Igh-V^{tm1(Igh-Vx24)Hmb}
• Name: immunoglobulin heavy chain variable region; targeted mutation 1, Dan Holmberg
• MGI ID: MGI:3701360
• Gene: Igh-V Location: unknown Genetic Position: Chr12, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:54380
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• A targeting vector was designed to replace VH 81X with the Igh-VX24 and a PGK-neo cassette. (J:54380)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igh-V Mutation: 5 strains or lines available

References

• Original: J:54380 Eriksson B, et al., Establishment and characterization of a mouse strain (TLL) that spontaneously develops T-cell lymphomas/leukemia. Exp Hematol. 1999 Apr;27(4):682-8
• All: 1 reference(s)