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Nmur2m1Hzg
Transgenic Allele Detail
Summary
Symbol: Nmur2m1Hzg
Name: neuromedin U receptor 2; mutation 1, Hongkui Zheng
MGI ID: MGI:3701426
Synonyms: NMUR2 KO
Gene: Nmur2  Location: Chr11:55915816-55931813 bp, - strand  Genetic Position: Chr11, 33.39 cM
Alliance: Nmur2m1Hzg page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:117649
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Transgene
description
Transgene Type:    Transgenic (Null/knockout)
Mutation:    Viral insertion
 
Mutation detailsA retroviral vector was inserted into the third intron and contained a splice acceptor, termination codons in all reading frames, a selection marker and a transcription terminator. This design would interrupt the transcript before exon 4, which contains TM7 of the 7-transmembrane domain and the C-terminal domain. RT-PCR confirmed absence of wild-type transcript in mutants. (J:117649)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmur2 Mutation:  28 strains or lines available
References
Original:  J:117649 Zeng H, et al., Neuromedin U receptor 2-deficient mice display differential responses in sensory perception, stress, and feeding. Mol Cell Biol. 2006 Dec;26(24):9352-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory