Nmur2m1Hzg
Transgenic Allele Detail
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Symbol: |
Nmur2m1Hzg |
Name: |
neuromedin U receptor 2; mutation 1, Hongkui Zheng |
MGI ID: |
MGI:3701426 |
Synonyms: |
NMUR2 KO |
Gene: |
Nmur2 Location: Chr11:55915816-55931813 bp, - strand Genetic Position: Chr11, 33.39 cM
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Alliance: |
Nmur2m1Hzg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:117649
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129/Sv
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Transgene Type: |
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Transgenic (Null/knockout) |
Mutation: |
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Viral insertion
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Mutation details: A retroviral vector was inserted into the third intron and contained a splice acceptor, termination codons in all reading frames, a selection marker and a transcription terminator. This design would interrupt the transcript before exon 4, which contains TM7 of the 7-transmembrane domain and the C-terminal domain. RT-PCR confirmed absence of wild-type transcript in mutants.
(J:117649)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nmur2 Mutation: |
28 strains or lines available
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Original: |
J:117649 Zeng H, et al., Neuromedin U receptor 2-deficient mice display differential responses in sensory perception, stress, and feeding. Mol Cell Biol. 2006 Dec;26(24):9352-63 |
All: |
1 reference(s) |
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