Gapdh^M5Neu
Chemically induced Allele Detail

Summary

• Symbol: Gapdh^M5Neu
• Name: glyceraldehyde-3-phosphate dehydrogenase; mutation 5, Neuherberg
• MGI ID: MGI:3701514
• Synonyms: GAPDH3929
• Gene: Gapdh Location: Chr6:125138812-125143450 bp, - strand Genetic Position: Chr6, 59.32 cM, cytoband C
• Alliance: Gapdh^M5Neu page

Mutation origin

• Strain of Origin: (101 x C3H)F1 X T-stock

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Single point mutation
• Mutation details: This N-methyl-N-nitrosourea- (MNU-) induced mutation is a G-to-A transition at codon 167, predicted to replace glycine (GGC) with aspartic acid (GAC) (G167D), in exon 3. (J:126359)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gapdh Mutation: 41 strains or lines available

References

• Original: J:126359 Pretsch W, et al., Genetic, biochemical, and molecular characterization of nine glyceraldehyde-3-phosphate dehydrogenase mutants with reduced enzyme activity in Mus musculus. Mamm Genome. 2007 Oct;18(10):686-92
• All: 1 reference(s)