Gpr39^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gpr39^tm1Dgen
• Name: G protein-coupled receptor 39; targeted mutation 1, Deltagen
• MGI ID: MGI:3701833
• Gene: Gpr39 Location: Chr1:125604732-125801599 bp, + strand Genetic Position: Chr1, 54.7 cM, cytoband E3
• Alliance: Gpr39^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119239
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Nucleotides 278-647 of the open reading frame were replaced with a neo cassette. RT-PCR confirmed the absence of transcript in the stomach and colon (normal expression domains). (J:119239)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr39 Mutation: 28 strains or lines available

References

• Original: J:119239 Tremblay F, et al., Normal food intake and body weight in mice lacking the G protein-coupled receptor GPR39. Endocrinology. 2007 Feb;148(2):501-6
• All: 13 reference(s)