Lap3tm1Klr
Targeted Allele Detail
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| Symbol: |
Lap3tm1Klr |
| Name: |
leucine aminopeptidase 3; targeted mutation 1, Kenneth L Rock |
| MGI ID: |
MGI:3702002 |
| Synonyms: |
LAP- |
| Gene: |
Lap3 Location: Chr5:45650716-45670033 bp, + strand Genetic Position: Chr5, 24.98 cM
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| Alliance: |
Lap3tm1Klr page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:119392
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
(129 x C57BL/6)F1
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1-13 (19.2kb) were replaced with a lacZ-neo cassette creating a null allele. The absence of protein product was confirmed by western blot of MEFs with or without IFN treatment.
(J:119392)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Lap3 Mutation: |
37 strains or lines available
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| Original: |
J:119392 Towne CF, et al., Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol. 2005 Nov 15;175(10):6605-14 |
| All: |
2 reference(s) |
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Analysis Tools
