Mesp1^tm4Ysa
Targeted Allele Detail

Summary

• Symbol: Mesp1^tm4Ysa
• Name: mesoderm posterior 1; targeted mutation 4, Yukimo Saga
• MGI ID: MGI:3702007
• Synonyms: DE1
• Gene: Mesp1 Location: Chr7:79441989-79443338 bp, - strand Genetic Position: Chr7, 45.16 cM
• Alliance: Mesp1^tm4Ysa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:71983
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame and 6kb of upstream sequence, including the EME and DE1 enhancers, was replaced with a neo cassette. (J:71983)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mesp1 Mutation: 18 strains or lines available

References

• Original: J:71983 Haraguchi S, et al., Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development. Mech Dev. 2001 Oct;108(1-2):59-69
• All: 1 reference(s)