Mesp2^{tm7(mespb)Ysa}
Targeted Allele Detail

Summary

• Symbol: Mesp2^{tm7(mespb)Ysa}
• Name: mesoderm posterior 2; targeted mutation 7, Yumiko Saga
• MGI ID: MGI:3702191
• Synonyms: neo-mespb
• Gene: Mesp2 Location: Chr7:79460475-79463179 bp, + strand Genetic Position: Chr7, 45.18 cM
• Alliance: Mesp2^{tm7(mespb)Ysa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75945
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutation: Insertion
• Mesp2^{tm7(mespb)Ysa} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  zebrafish

  mespba (58070)

  Mesp1	(MGI:107785)
  Mesp2	(MGI:1096325)

• Mutation details: The mouse gene was replaced with the open reading frame of zebrafish mespb followed by a floxed-neo cassette. (J:75945)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mesp2 Mutation: 30 strains or lines available

References

• Original: J:75945 Nomura-Kitabayashi A, et al., Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development. 2002 May;129(10):2473-81
• All: 1 reference(s)