Tg(Thy1-cre)703Vaw
Transgene Detail

Summary

• Symbol: Tg(Thy1-cre)703Vaw
• Name: transgene insertion 703, Valerie A Wallace
• MGI ID: MGI:3702324
• Synonyms: Tg(Thy1-cre)729Vaw, Thy1-Cre
• Transgene: Tg(Thy1-cre)703Vaw Location: unknown
• Alliance: Tg(Thy1-cre)703Vaw page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Thy1-cre)703Vaw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Thy1

• Mutation details: A 1.1kb Cre-containing cDNA fragment was fused to the Thy promoter from the Thy-1.2 expression cassette. Crosses to Z/AP or ROSA reporter mice and subsequent beta-galactosidase staining assays were used to tested transgene insertion. Twelve independent lines derived from eleven founder mice exhibit variable expression in retinal neuroblast layer, retinal ganglion cell layer, cortex neuroblast layer and cortex postmitotic cells, cerebellum external ganglion layer, cerebellum Purkinje cell layer, cerebellum granule cell layer, the choroid plexus, spinal cord and dorsal root ganglia. This record describes line 729 and is a representative record for all lines. (J:77070)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Thy1 (species not specified) Summary of all recombinase alleles driven by Thy1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77070 Campsall KD, et al., Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice. Dev Dyn. 2002 Jun;224(2):135-43
• All: 7 reference(s)