Tg(Prm1-cre)1Mrc
Transgene Detail

Summary

• Symbol: Tg(Prm1-cre)1Mrc
• Name: transgene insertion 1, Mario R Capecchi
• MGI ID: MGI:3702329
• Synonyms: Prm1-Cre-hGH
• Transgene: Tg(Prm1-cre)1Mrc Location: unknown
• Alliance: Tg(Prm1-cre)1Mrc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prm1-cre)1Mrc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prm1 (MGI:97765)

• Mutation details: The mouse promoter was used to drive spermatid-specific expression of the P1 cre cistron followed by a human growth hormone 3' flanking sequence. Several lines were created (no line names given). Expression of the cre transgene in testes was confirmed by RNase protection assay. (J:66393)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prm1 (mouse) Summary of all recombinase alleles driven by Prm1. Alliance mouse Prm1 gene page

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:66393 Schmidt EE, et al., Illegitimate cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13702-7
• All: 1 reference(s)