Ucn3^tm1Pbl
Targeted Allele Detail

Summary

• Symbol: Ucn3^tm1Pbl
• Name: urocortin 3; targeted mutation 1, Wylie Vale
• MGI ID: MGI:3702546
• Gene: Ucn3 Location: Chr13:3990688-3995349 bp, - strand Genetic Position: Chr13, 2.2 cM, cytoband A1
• Alliance: Ucn3^tm1Pbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119417
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance cassette was inserted into exon 2. Absence of protein was confirmed by in situ hybridization. (J:119417)

Expression

In Mice Carrying this Mutation:	7 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ucn3 Mutation: 21 strains or lines available

References

• Original: J:119417 Li C, et al., Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4206-11
• All: 8 reference(s)