Dok7^tm1Yyam
Targeted Allele Detail

Summary

• Symbol: Dok7^tm1Yyam
• Name: docking protein 7; targeted mutation 1, Yuji Yamanashi
• MGI ID: MGI:3702943
• Synonyms: Dok-7^-
• Gene: Dok7 Location: Chr5:35214110-35245183 bp, + strand Genetic Position: Chr5, 18.0 cM
• Alliance: Dok7^tm1Yyam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110011
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1 and 2 were replaced with a neomycin resistance cassette. (J:110011)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dok7 Mutation: 30 strains or lines available

References

• Original: J:110011 Okada K, et al., The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science. 2006 Jun 23;312(5781):1802-5
• All: 1 reference(s)