Isx^tm1Shiv
Targeted Allele Detail

Summary

• Symbol: Isx^tm1Shiv
• Name: intestine specific homeobox; targeted mutation 1, Ramesh A Shivadaani
• MGI ID: MGI:3703167
• Synonyms: Isx^-
• Gene: Isx Location: Chr8:75599801-75620134 bp, + strand Genetic Position: Chr8, 35.54 cM, cytoband C2
• Alliance: Isx^tm1Shiv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119560
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neomycin resistance cassette. Northern blot confirmed absence of transcript in mutant cecum and stomach samples. (J:119560)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Isx Mutation: 24 strains or lines available

References

• Original: J:119560 Choi MY, et al., A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
• All: 5 reference(s)