Tg(SV40/HTLV-FCER1A)1Bhk
Transgene Detail

Summary

• Symbol: Tg(SV40/HTLV-FCER1A)1Bhk
• Name: transgene insertion 1, Beverly H Koller
• MGI ID: MGI:3703557
• Synonyms: hFcepsilonRIalphaTg
• Transgene: Tg(SV40/HTLV-FCER1A)1Bhk Location: unknown
• Alliance: Tg(SV40/HTLV-FCER1A)1Bhk page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:113572
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(SV40/HTLV-FCER1A)1Bhk expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FCER1A (2205)

  Fcer1a

  (MGI:95494)

• Mutation details: To construct the transgene, the SV40 early promoter was positioned at the 5' end of the HTLV provirus promoter, leaving a truncated 5'LTR, and the SV40 polyadenylation sequence was placed at the 3'end to drive transcription of a human FCER1A cDNA. (J:113572)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

ES cell line = D3 (129S2/SvPas) or E14TG2a (129P2/OlaHsd).

References

• Original: J:113572 Dombrowicz D, et al., Anaphylaxis mediated through a humanized high affinity IgE receptor. J Immunol. 1996 Aug 15;157(4):1645-51
• All: 3 reference(s)