Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem
Transgene Detail

Summary

• Symbol: Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem
• Name: transgene insertion 23, Bernice Morrow
• MGI ID: MGI:3703643
• Synonyms: 316.23, BAC316.23, TBX1-BAC, Tg316, Tg(GNB1L,TBX1,GP1BB,SEPT5)23Rak
• Transgene: Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem Location: unknown
• Alliance: Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem expresses 4 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GNB1L (54584)

  Gnb1l

  (MGI:1338057)

  human

  GP1BB (2812)

  Gp1bb

  (MGI:107852)

  human

  SEPTIN5 (5413)

  Septin5

  (MGI:1195461)

  human

  TBX1 (6899)

  Tbx1	(MGI:98493)

• Mutation details: This is a BAC transgene where the inserted human BAC is from the RPCI11 library and contains four genes, GNB1l, TBX1, GP1BB, and SEPT5. (J:67796)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:67796 Merscher S, et al., TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 2001 Feb 23;104(4):619-29
• All: 5 reference(s)