Tg(Tagln-rtTA)E1Jwst
Transgene Detail

Summary

• Symbol: Tg(Tagln-rtTA)E1Jwst
• Name: transgene insertion E1, James West
• MGI ID: MGI:3703755
• Synonyms: SM22-rtTA
• Transgene: Tg(Tagln-rtTA)E1Jwst Location: unknown
• Alliance: Tg(Tagln-rtTA)E1Jwst page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgene has the 488-bp fragment of the murine smooth muscle-specific SM22-alpha (Tagln or transgelin) promoter to drive expression of the reverse tetracycline transactivator gene (rtTA). (J:98898)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:98898 West J, et al., Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res. 2004 Apr 30;94(8):1109-14
• All: 15 reference(s)