Tg(Nphs1-cre)2Seq
Transgene Detail

Summary

• Symbol: Tg(Nphs1-cre)2Seq
• Name: transgene insertion 2, Susan E Quaggin
• MGI ID: MGI:3703790
• Synonyms: Nephrin-cre (KV)
• Transgene: Tg(Nphs1-cre)2Seq Location: unknown
• Alliance: Tg(Nphs1-cre)2Seq page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Nphs1-cre)2Seq expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nphs1 (MGI:1859637)

• Mutation details: A mouse Neph1 promoter fused to a cre recombinase gene was used for the transgene. A 4.125 kb fragment of the mouse Neph1 promoter was used to drive transgene expression in podocytes. This construct was previously used to produce Tg(Nphs1-cre)1Seq. (J:82024)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nphs1 (mouse) Summary of all recombinase alleles driven by Nphs1. Alliance mouse Nphs1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:82024 Eremina V, et al., Glomerular-specific gene excision in vivo. J Am Soc Nephrol. 2002 Mar;13(3):788-93
• All: 3 reference(s)