Prdm1^tm2Masu
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm2Masu
• Name: PR domain containing 1, with ZNF domain; targeted mutation 2, M Azim Surani
• MGI ID: MGI:3703794
• Synonyms: Blimp1^fl, Blimp1 loxP
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm2Masu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99994
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo selection casset and an additional loxP site flanked exon5. The Neo cassette was then removed by Cre mediated excision. (J:99994)

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 66 strains or lines available

References

• Original: J:99994 Ohinata Y, et al., Blimp1 is a critical determinant of the germ cell lineage in mice. Nature. 2005 Jul 14;436(7048):207-13
• All: 11 reference(s)