Tg(Ins1-EGFP)1Hara
Transgene Detail

Summary

• Symbol: Tg(Ins1-EGFP)1Hara
• Name: transgene insertion 1, Manami Hara
• MGI ID: MGI:3704871
• Synonyms: MIP-EGFP, MIP-GFP, MIP:GFP, MIP-GFP (line 1), MIP-GFP (line1), Tg(Ins1-GFP)1Hara
• Transgene: Tg(Ins1-EGFP)1Hara Location: unknown
• Alliance: Tg(Ins1-EGFP)1Hara page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A transgenic construct containing the coding region of the EGFP gene and a 2.1kb sequence of the human growth hormone to confer high expression of the EGFP, under the control of the mouse insulin 1 gene promoter (a 8.5 kb region including -8.5 to +12 bp relative to the transcriptional start site) was injected into fertilized CD1 mouse eggs. Founder line 1 was subsequently established. Fluorescence is detected in tissues where insulin I is normally expressed; fluorescent protein expression in pancreatic beta-cells is evident from embryonic day (E)13.5 through adult. (J:99450)

Expression

In Mice Carrying this Mutation:

5 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:99450 Hara M, et al., Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E177-83
• All: 68 reference(s)