Tg(Ins1-EGFP)1Hara
Transgene Detail
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Symbol: |
Tg(Ins1-EGFP)1Hara |
Name: |
transgene insertion 1, Manami Hara |
MGI ID: |
MGI:3704871 |
Synonyms: |
MIP-EGFP, MIP-GFP, MIP:GFP, MIP-GFP (line 1), MIP-GFP (line1), Tg(Ins1-GFP)1Hara |
Transgene: |
Tg(Ins1-EGFP)1Hara Location: unknown
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Alliance: |
Tg(Ins1-EGFP)1Hara page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: A transgenic construct containing the coding region of the EGFP gene and a 2.1kb sequence of the human growth hormone to confer high expression of the EGFP, under the control of the mouse insulin 1 gene promoter (a 8.5 kb region including -8.5 to +12 bp relative to the transcriptional start site) was injected into fertilized CD1 mouse eggs. Founder line 1 was subsequently established. Fluorescence is detected in tissues where insulin I is normally expressed; fluorescent protein expression in pancreatic beta-cells is evident from embryonic day (E)13.5 through adult.
(J:99450)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:99450 Hara M, et al., Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E177-83 |
All: |
66 reference(s) |
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