Tg(Lbx1-cre)3Cbm
Transgene Detail

Summary

• Symbol: Tg(Lbx1-cre)3Cbm
• Name: transgene insertion 3, Carmen Birchmeier
• MGI ID: MGI:3704929
• Synonyms: Lbx1^cre, Tg(Lbx1-cre)3Joe
• Transgene: Tg(Lbx1-cre)3Cbm Location: unknown
• Alliance: Tg(Lbx1-cre)3Cbm page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Lbx1-cre)3Cbm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lbx1 (MGI:104867)

• Mutation details: Cre recombinase was inserted after the initiating ATG of Lbx1 in a 144 kb mouse BAC (clone RP23-188J8). Cre recombinase activity is seen in muscle progenitor cells that migrate to the limbs and branchial arches. (J:120053)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lbx1 (mouse) Summary of all recombinase alleles driven by Lbx1. Comparative matrix view of recombinase activities Alliance mouse Lbx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:120053 Vasyutina E, et al., RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4443-8
• All: 3 reference(s)