H1f7^tm1Yoni
Targeted Allele Detail

Summary

• Symbol: H1f7^tm1Yoni
• Name: H1.7 linker histone; targeted mutation 1, Yoshitake Nishimune
• MGI ID: MGI:3704974
• Gene: H1f7 Location: Chr15:98153867-98155174 bp, - strand Genetic Position: Chr15, 54.26 cM
• Alliance: H1f7^tm1Yoni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119846
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The intronless gene was replaced with a neo cassette. The absence of the protein was confirmed by western blot analysis of testicular lysate of adult homozygotes. (J:119846)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H1f7 Mutation: 20 strains or lines available

References

• Original: J:119846 Tanaka H, et al., HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility. Mol Cell Biol. 2005 Aug;25(16):7107-19
• All: 1 reference(s)