Rims2^tm1.1Schc
Targeted Allele Detail

Summary

• Symbol: Rims2^tm1.1Schc
• Name: regulating synaptic membrane exocytosis 2; targeted mutation 1.1, Susanne Schoch
• MGI ID: MGI:3706333
• Synonyms: Rim2alpha^-, Rims2^mt
• Gene: Rims2 Location: Chr15:39061681-39547768 bp, + strand Genetic Position: Chr15, 15.45 cM, cytoband C
• Alliance: Rims2^tm1.1Schc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119934
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 5 was removed via cre mediated recombination. (J:119934)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rims2 Mutation: 250 strains or lines available

References

• Original: J:119934 Schoch S, et al., Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. EMBO J. 2006 Dec 13;25(24):5852-63
• All: 5 reference(s)