Krt25^Rgsc573
Chemically induced Allele Detail

Summary

• Symbol: Krt25^Rgsc573
• Name: keratin 25; RIKEN Genomic Sciences Center (GSC), 573
• MGI ID: MGI:3707007
• Synonyms: M100573
• Gene: Krt25 Location: Chr11:99206342-99213777 bp, - strand Genetic Position: Chr11, 62.92 cM
• Alliance: Krt25^Rgsc573 page

Mutation origin

• Strain of Origin: (DBA/2J x C57BL/6J)F1
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This allele contains a single nonsynonymous base substitution , 1135 T to A, that results in an amino acid substitution of asparagine for tyrosine at position 379 (Y379N). (J:130100)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Krt25 Mutation: 28 strains or lines available

References

• Original: J:130597 Masuya H, et al., Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program. Mamm Genome. 2005 Nov;16(11):829-37
• All: 3 reference(s)