Ddb2^tm1Vri
Targeted Allele Detail

Summary

• Symbol: Ddb2^tm1Vri
• Name: damage specific DNA binding protein 2; targeted mutation 1, Harry Vrieling
• MGI ID: MGI:3707217
• Synonyms: Ddb2^-
• Gene: Ddb2 Location: Chr2:91041917-91067327 bp, - strand Genetic Position: Chr2, 50.56 cM, cytoband E1
• Alliance: Ddb2^tm1Vri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103406
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 4-7 were replaced with a puromycin resistance cassette. (J:103406)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddb2 Mutation: 38 strains or lines available

References

• Original: J:103406 Alekseev S, et al., Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation. Cancer Res. 2005 Nov 15;65(22):10298-306
• All: 2 reference(s)