Cd40^tm1Arah
Targeted Allele Detail

Summary

• Symbol: Cd40^tm1Arah
• Name: CD40 antigen; targeted mutation 1, Amin Rahemtulla
• MGI ID: MGI:3707600
• Synonyms: CD40^-
• Gene: Cd40 Location: Chr2:164897535-164913574 bp, + strand Genetic Position: Chr2, 85.38 cM
• Alliance: Cd40^tm1Arah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120512
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into exon 3. (J:120512)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd40 Mutation: 53 strains or lines available

References

• Original: J:120512 Ensminger SM, et al., Critical role for IL-4 in the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation. J Immunol. 2001 Jul 1;167(1):532-41
• All: 1 reference(s)